The Hormone Leptin and appetite regulation.
A major key to weight control, is it Leptin?
Leptin is a hormone produced by the fat cells. It is responsible for managing metabolism, weight management, and hormone balance. Leptin influences the brain and it controls energy, appetite and metabolic rate. Leptin problems can cause a person to eat too much, and is responsible for compromised metabolism, food cravings, food obsessions and can contribute to heart disease.
Leptin?s Role in Weight Management
Leptin is the key hormone that regulates appetite and weight loss by managing satiety, appetite control, metabolism and blood sugar.
Leptin tells your brain when to eat, how much to eat and most importantly when to stop eating.
Overweight people have high levels of leptin in their blood yet are resistant to its effects, known as ?Leptin resistance?
Reducing Leptin resistance and serum Leptin levels enhances Leptin function which is critical to successful weight management by lowering total body fat.
The Leptin Hormone has a significant influence on the following:
Leptin?s Role in Metabolic Wellness
Leptin resistance has been shown to exacerbate symptoms of metabolic syndrome (blood lipids, blood sugar and inflammation which are also known promoters of premature aging).
Researchers have also found that Leptin resistance may also hinder weight loss. Leptin resistance is a chronic inflammatory problem that can lead to slow, steady weight gain. Researchers have discovered that C-Reactive Protein can bind to Leptin, preventing Leptin from being able to regulate hunger.
When people gain weight, it increases the production of CRP
This is low level, chronic inflammation that can contribute to chronic, degenerative diseases such as:
- Auto-immune diseases in general
- Irritable Bowel Syndrome (IBS) and other GI diseases
- Dementia / Alzheimer?s
- Insulin Resistance / Diabetes
The term leptin resistance refers to this binding of leptin by C-Reactive Protein (CRP).
Because Leptin is the major signaling hormone that tells our brain that we are satiated (full).IF Nitric Oxide levels are low the signaling sequence is impeded.
This means Leptin is unable to get into the brain across the blood / brain barrier, which means that people lose their sense of satiety.
THIS IS WHY PEOPLE KEEP EATING WHEN THEY ARE FULL AND GO ON CARBOHYDRATE BINGES...
Research has indicated that after weight loss, changes in the hormones that control hunger and weight gain occur, including a decrease in Leptin levels in the brain. These changes can increase hunger, and can cause a person?s metabolism to slow down. These hormonal changes may explain why so many attempts at weight loss end up in a yo-yo effect of weight loss and subsequent weight gain.
THE key to long term healthy weight management is Leptin balance by eating foods with a high nutrient DENSITY
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